Valium - Manodiazo-10 Diazepam 150 x 10mg (Valium) - RoidSupply.com - Cheap Steroids Direct to UK

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Products: 132
Categories: 35
Prices: British Pounds

Location: /Valium

Product Information

Brand: Marich
Name: Manodiazo-10
Chemical: Diazepam (Valium)
Strength: 10mg
Quantity: 150 Tabs

Facts:

Diazepam was the second benzodiazepine to be invented by Sternbach of Hoffmann-La Roche, and was approved for use in 1960. In 1963 its improved version, Valium, was released and was incredibly popular, helping Roche to become a pharmaceutical industry giant. It is two and a half times more potent than its predecessor, chlordiazepoxide, which it quickly surpassed in terms of sales. After this initial success, other pharmaceutical companies began to introduce other benzodiazepine derivatives.

The benzodiazepines gained popularity among medical professionals as an improvement upon barbiturates, which have a comparatively narrow therapeutic index, and are far more sedating at therapeutic doses. The benzodiazepines are also far less dangerous; death rarely results from diazepam overdose, except in cases where it is consumed with large amounts of other depressants (such as alcohol or other sedatives).

Diazepam was the top-selling pharmaceutical in the United States from 1969 to 1982, with peak sales in 1978 of 2.3 billion tablets. Diazepam—along with oxazepam, nitrazepam, and temazepam—represents 82% of the benzodiazepine market in Australia. While psychiatrists continue to prescribe diazepam for the short-term relief of anxiety, neurology has taken the lead in prescribing diazepam for the palliative treatment of certain types of epilepsy and spastic activity, e.g., forms of paresis. It is also the first line of defense for a rare disorder called stiff-person syndrome.

Diazepam is mainly used to treat anxiety, insomnia, and symptoms of acute alcohol or opiate withdrawal. It is also used as a premedication for inducing sedation, anxiolysis or amnesia before certain medical procedures.

Diazepam is rarely used for the long-term treatment of epilepsy because tolerance to the anticonvulsant effects of diazepam usually develops within 6 to 12 months of treatment, effectively rendering it useless for this purpose.

Interactions

Diazepam has a broad spectrum of indications (most of which are off-label), including:

    * Treatment of anxiety, panic attacks, and states of agitation
    * Treatment of status epilepticus, adjunctive treatment of other forms of epilepsy
    * Treatment of neurovegetative symptoms associated with vertigo
    * Treatment of the symptoms of alcohol, opiate and benzodiazepine withdrawal
    * Short-term treatment of insomnia
    * Treatment of tetanus, together with other measures of intensive-treatment
    * Adjunctive treatment of spastic muscular paresis (para-/tetraplegia) caused by cerebral or spinal cord conditions such as stroke, multiple sclerosis, spinal cord injury (long-term treatment is coupled with other rehabilitative measures)
    * Palliative treatment of stiff person syndrome
    * Pre-/postoperative sedation, anxiolysis and/or amnesia (e.g., before endoscopic or surgical procedures)
    * Treatment of overdosage with hallucinogens or CNS stimulants
    * Adjunctive treatment of drug-induced seizures, resulting from exposure to sarin, VX, soman, lindane, chloroquine, physostigmine, or pyrethroids
    * Emergency treatment of eclampsia, along with IV magnesium sulfate
    * Prophylactic treatment of oxygen toxicity during hyperbaric oxygen therapy
    * Used in the treatment for irritable bowel syndrome
    * Used to treat pain resulting from muscle spasms caused by various dystonias, including blepharospasm

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